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Longitudinal changes in ox-LDL, Trx, E-selectin, P-selectin, ICAM-1, and VCAM-1 during 24-month rhGH therapy at baseline, 12 months, and 24 months. Statistical significance is indicated by asterisks: * p < 0.05 vs. baseline; *** p < 0.001 vs. baseline; **** p < 0.00001 vs. baseline.

Journal: International Journal of Molecular Sciences

Article Title: Twenty-Four-Month rhGH Intervention: Insights into Redox Regulation, Vascular Biomarkers, and Body Composition in Adult GHD Patients

doi: 10.3390/ijms27031451

Figure Lengend Snippet: Longitudinal changes in ox-LDL, Trx, E-selectin, P-selectin, ICAM-1, and VCAM-1 during 24-month rhGH therapy at baseline, 12 months, and 24 months. Statistical significance is indicated by asterisks: * p < 0.05 vs. baseline; *** p < 0.001 vs. baseline; **** p < 0.00001 vs. baseline.

Article Snippet: OS and endothelial markers were quantified using commercially available enzyme-linked immunosorbent assay (ELISA) kits according to the manufacturers’ instructions: ox-LDL (Novus Biologicals, Bio-Techne, NBP3-18794; Minneapolis, MN, USA), Trx (XpressBio, XPEH0291; Frederick, MD, USA), OGG1 (Cloud-Clone Corp., SEC704Hu; Wuhan, China), VCAM-1 (Cloud-Clone Corp., SEA547Hu; Wuhan, China), ICAM-1 (Cloud-Clone Corp., SEA548Ca; Wuhan, China), and E-selectin (Cloud-Clone Corp., SEA029Hu; Wuhan, China).

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